Smallheer, Joanne M.: search on Z-Library

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1

Factor XIa Inhibitors as New Anticoagulants

Quan, Mimi L., Pinto, Donald J. P., Smallheer, Joanne M., Ewing, William R., Rossi, Karen A., Luettgen, Joseph M., Seiffert, Dietmar A., Wexler, Ruth R.

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 13.86 MB

english, 2018

2

A new approach to 4-substituted indoles

Maehr, Hubert, Smallheer, Joanne M.

Journal:

Journal of Organic Chemistry

Year:

1981

Language:

english

File:

PDF, 631 KB

english, 1981

3

Synthesis of d-arabinose 5-phosphate and d-xylose 5-phosphate

Hubert Maehr, Joanne Smallheer

Journal:

Carbohydrate Research

Year:

1978

Language:

english

File:

PDF, 542 KB

english, 1978

4

Total Synthesis of (.+-.)-Dragmacidin: A Cytotoxic Bis(indole)alkaloid of Marine Origin

Jiang, Biao, Smallheer, Joanne M., Amaral-Ly, Carol, Wuonola, Mark A.

Journal:

Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 619 KB

english, 1994

5

Total syntheses of rivularins D1 and D3

Maehr, Hubert, Smallheer, Joanne

Journal:

Journal of the American Chemical Society

Year:

1985

Language:

english

File:

PDF, 433 KB

english, 1985

6

Pyrazole-based factor Xa inhibitors containing N-arylpiperidinyl P4 residues

Jennifer X. Qiao, Xuhong Cheng, Joanne M. Smallheer, Robert A. Galemmo, Spencer Drummond, Donald J.P. Pinto, Daniel L. Cheney, Kan He, Pancras C. Wong, Joseph M. Luettgen, Robert M. Knabb, Ruth R. Wex

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 414 KB

english, 2007

7

[Annual Reports in Medicinal Chemistry] Annual Reports in Medicinal Chemistry Volume 44 Volume 44 || Chapter 9 Recent Advances in Coagulation Serine Protease Inhibitors

Smallheer, Joanne M.

Year:

2009

Language:

english

File:

PDF, 1.05 MB

english, 2009

8

N,N-[(4-nitro-1H-inden-1-ylidene)methyl]dialkylamines by an unexpected reaction

Maehr, Hubert, Smallheer, Joanne, Blount, John F., Todaro, Louis J.

Journal:

Journal of Organic Chemistry

Year:

1981

Language:

english

File:

PDF, 384 KB

english, 1981

9

Functionalized aliphatic P2/P2′ analogs of HIV-1 protease inhibitor DMP323

Joanne M. Smallheer, Robert J. McHugh, Chong-Hwan Chang, Robert F. Kaltenbach III, Tabitha V. Worley, Ronald M. Klabe, Lee T. Bacheler, Marlene M. Rayner, Susan Erickson-Viitanen, Steven P. Seitz

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 432 KB

english, 1997

10

Identification and characterization of antibodies that bind GPIIb/IIIa: Antagonist complexes

Leah Breth, Jennifer Kochie, Amanda Combs, Shuaige Wang, Joanne Smallheer, Jeffrey Billheimer, Dietmar Seiffert, Gregory Hollis, Karyn O'Neil

Journal:

Journal of Immunological Methods

Year:

2005

Language:

english

File:

PDF, 271 KB

english, 2005

11

Microbial products. VI. Five novel metabolites related to benz(A)anthracene from an unidentified actinomycete designated X-14881.

MAEHR, HUBERT, LIU, CHAO-MIN, LIU, MARK, PERROTTA, AGOSTINO, SMALLHEER, JOANNE M., WILLIAMS, THOMAS H., BLOUNT, JOHN F.

Journal:

The Journal of Antibiotics

Year:

1982

Language:

english

File:

PDF, 2.59 MB

english, 1982

12

Structure based design of macrocyclic factor XIa inhibitors: Discovery of cyclic P1 linker moieties with improved oral bioavailability

Clark, Charles G., Rossi, Karen A., Corte, James R., Fang, Tianan, Smallheer, Joanne M., De Lucca, Indawati, Nirschl, David S., Orwat, Michael J., Pinto, Donald J.P., Hu, Zilun, Wang, Yufeng, Yang, Wu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2019

File:

PDF, 2.04 MB

2019

13

Synthesis and Biological Evaluation of Nonpeptide Integrin Antagonists Containing Spirocyclic Scaffolds.

Joanne M. Smallheer, Carolyn A. Weigelt, Francis J. Woerner, Jennifer S. Wells, Wayne F. Daneker, Shaker A. Mousa, Ruth R. Wexler, Prabhakar K. Jadhav

Journal:

Year:

2004

File:

PDF, 99 KB

2004

14

Microbial products. II. Granaticinic acid, a new antibiotic from a thermophilic streptomycete

Hubert Maehr, Hilda V. Cuellar, Joanne Smallheer, Thomas H. Williams, Gino J. Sasso, Julius Berger

Journal:

Monatshefte für Chemie - Chemical Monthly

Year:

1979

Language:

english

File:

PDF, 464 KB

english, 1979

15

[Annual Reports in Medicinal Chemistry] Volume 35 || Chapter 10. Antiplatelet therapies

Smallheer, Joanne M.

Year:

2000

Language:

english

File:

PDF, 1.14 MB

english, 2000

16

Tetrahydroquinoline Derivatives as Potent and Selective Factor XIa Inhibitors

Quan, Mimi L., Wong, Pancras C., Wang, Cailan, Woerner, Francis, Smallheer, Joanne M., Barbera, Frank A., Bozarth, Jeffrey M., Brown, Randi L., Harpel, Mark R., Luettgen, Joseph M., Morin, Paul E., Pe

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.17 MB

english, 2014

17

Promotion of Softening and Ethylene Synthesis in Bartlett Pears by 3-Methylene Oxindole

Chaim Frenkel, Virginia R. Haddon and Joanne M. Smallheer

Journal:

PLANT PHYSIOLOGY

Year:

1975

Language:

english

File:

PDF, 454 KB

english, 1975

18

Chemistry of the gentamicins. III. A comment on the structure of gentamicin A.

MAEHR, HUBERT, SMALLHEER, JOANNE, SCHAFFNER, CARL P.

Journal:

The Journal of Antibiotics

Year:

1980

Language:

english

File:

PDF, 1.41 MB

english, 1980

19

Substituted pyrimidines. II. 1,3-Dimethylisocytosine and related compounds

Hubert Maehr, Joanne Smallheer, Voldemar Toome

Journal:

Journal of Heterocyclic Chemistry

Year:

1977

File:

PDF, 268 KB

1977

20

Microbial products. IV. X-14847, a new aminoglycoside from Micromonospora echinospora.

MAEHR, HUBERT, LIU, CHAO-MIN, HERMANN, THERON, PROSSER, BARBARA LA T., SMALLHEER, JOANNE M., PALLERONI, NORBERTO J.

Journal:

The Journal of Antibiotics

Year:

1980

Language:

english

File:

PDF, 2.51 MB

english, 1980

21

Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties

Pinto, Donald J.P., Smallheer, Joanne M., Corte, James R., Austin, Erin J.D., Wang, Cailan, Fang, Tianan, Smith, Leon M., Rossi, Karen A., Rendina, Alan R., Bozarth, Jeffrey M., Zhang, Ge, Wei, Anzhi,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 2.03 MB

english, 2015

22

SAR and factor IXa crystal structure of a dual inhibitor of factors IXa and Xa

Joanne M. Smallheer, Richard S. Alexander, Jianmin Wang, Shuaige Wang, Suanne Nakajima, Karen A. Rossi, Angela Smallwood, Frank Barbera, Debra Burdick, Joseph M. Luettgen, Robert M. Knabb, Ruth R. Wex

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 331 KB

english, 2004

23

Structure based design of macrocyclic factor XIa inhibitors: Discovery of cyclic P1 linker moieties with improved oral bioavailability

Clark, Charles G., Rossi, Karen A., Corte, James R., Fang, Tianan, Smallheer, Joanne M., De Lucca, Indawati, Nirschl, David S., Orwat, Michael J., Pinto, Donald J.P., Hu, Zilun, Wang, Yufeng, Yang, Wu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2019

Language:

english

File:

PDF, 2.04 MB

english, 2019

24

Microbial products. III. Epi-deoxynegamycin from a Micromonospora.

MAEHR, HUBERT, SMALLHEER, JOANNE, CHIN, MARCIA, PALLERONI, NORBERTO, WEISS, FLORENCE, LIU, CHAO-MIN

Journal:

The Journal of Antibiotics

Year:

1979

Language:

english

File:

PDF, 1.17 MB

english, 1979

25

Factor Xa Inhibitors: Next-Generation Antithrombotic Agents

Pinto, Donald J. P., Smallheer, Joanne M., Cheney, Daniel L., Knabb, Robert M., Wexler, Ruth R.

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 4.71 MB

english, 2010

26

Isoxazolines as Potent Antagonists of the Integrin α v β 3

Pitts, William J., Wityak, John, Smallheer, Joanne M., Tobin, A. Ewa, Jetter, James W., Buynitsky, Jennifer S., Harlow, Patricia P., Solomon, Kimberly A., Corjay, Martha H., Mousa, Shaker A., Wexler,

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 275 KB

english, 2000

27

Microbial products. VIII. Azinothricin, a novel hexadepsipeptide antibiotic.

MAEHR, HUBERT, LIU, CHAO-MIN, PALLERONI, NORBERTO J., SMALLHEER, JOANNE, TODARO, LOUIS, WILLIAMS, THOMAS H., BLOUNT, JOHN F.

Journal:

The Journal of Antibiotics

Year:

1986

Language:

english

File:

PDF, 4.18 MB

english, 1986

28

SAR and Factor IXa Crystal Structure of a Dual Inhibitor of Factors IXa and Xa.

Joanne M. Smallheer, et al. et al.

Journal:

Year:

2005

File:

PDF, 18 KB

2005

29

Synthesis of 1,5-dimethyl-1,4-dihydropyrrolo[3,4-b]-pyrrol-6(5H)-one by intramolecular Diels-Alder reaction to the imidazole nucleus.

Mark A. Wuonola, Joanne M. Smallheer

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 137 KB

english, 1992

30

Sulfonamidolactam inhibitors of coagulation factor Xa

Joanne M. Smallheer, Shuaige Wang, Mia L. Laws, Suanne Nakajima, Zilun Hu, Wei Han, Irina Jacobson, Joseph M. Luettgen, Karen A. Rossi, Alan R. Rendina, Robert M. Knabb, Ruth R. Wexler, Patrick Y.S. L

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 273 KB

english, 2008

31

Microbial products. 5. Absolute configuration of aminoglycoside X-14847

Maehr, Hubert, Smallheer, Joanne M., Blount, John F.

Journal:

Journal of Organic Chemistry

Year:

1981

Language:

english

File:

PDF, 531 KB

english, 1981

32

Intramolecular diels-alder reactions of isoquinoline-1-carboxamides

Mark A. Wuonola, Joanne M. Smallheer, J.M. Read, J.C. Calabrese

Journal:

Tetrahedron Letters

Year:

1991

Language:

english

File:

PDF, 264 KB

english, 1991

33

Synthesis and biological evaluation of nonpeptide integrin antagonists containing spirocyclic scaffolds

Joanne M. Smallheer, Carolyn A. Weigelt, Francis J. Woerner, Jennifer S. Wells, Wayne F. Daneker, Shaker A. Mousa, Ruth R. Wexler, Prabhakar K. Jadhav

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 175 KB

english, 2004

34

Rivularins. Preliminary synthetic studies

Maehr, Hubert, Smallheer, Joanne M.

Journal:

Journal of Organic Chemistry

Year:

1984

Language:

english

File:

PDF, 637 KB

english, 1984

35

Phenylimidazoles as Potent and Selective Inhibitors of Coagulation Factor XIa with in Vivo Antithrombotic Activity

Hangeland, Jon J., Friends, Todd J., Rossi, Karen A., Smallheer, Joanne M., Wang, Cailan, Sun, Zhong, Corte, James R., Fang, Tianan, Wong, Pancras C., Rendina, Alan R., Barbera, Frank A., Bozarth, Jef

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 3.53 MB

english, 2014

36

Synthetic (S)-5-(benzoyloxy)-6-oxohexanoic acid ethyl ester and [S,S-(E)-3-(hydroxymethyl)oxiranebutanoic acid methyl ester, important synthons for leukotrienes B4 and A4, from D-arabinose

Maehr, Hubert, Perrotta, Agostino, Smallheer, Joanne

Journal:

Journal of Organic Chemistry

Year:

1988

Language:

english

File:

PDF, 726 KB

english, 1988

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